Two Amyloid States of the Prion Protein Display Significantly Different Folding Patterns
نویسندگان
چکیده
منابع مشابه
Two amyloid States of the prion protein display significantly different folding patterns.
It has been well established that a single amino acid sequence can give rise to several conformationally distinct amyloid states. The extent to which amyloid structures formed within the same sequence are different, however, remains unclear. To address this question, we studied two amyloid states (referred to as R- and S-fibrils) produced in vitro from highly purified full-length recombinant pr...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2010
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2010.05.051